Interpretation of Experiments on Metabolic processes, using Isotopic Tracer Elements
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چکیده
منابع مشابه
Mechanism of the propionyl carboxylase reaction. II. Isotopic exchange and tracer experiments.
Experiments with bicarbonate-C4 or methylmalonyl coenzyme A-3-C14 and substrate amounts of crystalline propionyl carboxylase (1) demonstrated unequivocally that the over-all reaction involves carboxylation and decarboxylation of the enzyme according to Reactions 1 and 2. Reaction 1 itself had previously been believed (4-6) to consist of two separate steps. However, careful reinvestigation of th...
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15 صفحه اولEquations for tracer experiments.
The use of isotopes makes possible quantitative measurements of many biochemical and physiological processes, hitherto secure from such detailed observation. Perhaps the most frequent use of this tool is in the observations of physiology that are concerned with the transfer of fluid from one portion of the body to another, and in the biochemical observations of the formation of one compound fro...
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ژورنال
عنوان ژورنال: Nature
سال: 1948
ISSN: 0028-0836,1476-4687
DOI: 10.1038/162963b0